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The group with neither TDF nor EFV before and after switch to DOR experienced a more modest, statistically significant weight loss (-0.72 kg/yr

Isatuximab binds to the CD38 epitope via its gamma heavy chains, inducing cell death through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and apoptosis 146,147

53, PL291296

Body composition (where measurable, by DEXA or similar), waist circumference, subjective energy and recovery, and any side-effect profile changes are others