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Novel homodimer metabolites of GDC-0994 via cytochrome P450-catalyed radical coupling Source: Drug Metab Dispos

Functional group manipulation using organoselenium reagents

Furthermore, the model demonstrated increased resistance to cerulenin, a fatty acid synthase inhibitor, and lower levels of condensing enzymes linked to the synthesis of very long-chain fatty acids (Visram et al., 2018)