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These dietary choices limit natural sources of B12 to animal products, leading to deficiencies in up to 90% of people adhering to these diets

5-Amino-1MQ is a small molecule that inhibits the NNMT enzyme to boost NAD+ levels, while MOTS-c is a mitochondrial peptide that activates the AMPK pathway, mimicking exercise

By blocking NNMT, the compound is associated with preserved NAD+ levels and reduced fat storage, alongside improvements in cellular energy utilization and insulin sensitivity