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Bull Biol Allied Sci Res 2021(1):3636

One features Berberine with Milk Thistle and Turmeric, while the other combines L-Carnitine, Green Coffee Bean, Black Pepper, and L-Theanine in vegetarian capsules

Individuals with MetS are three times more likely to have a heart attack or stroke due to atherosclerosis [2]

Furthermore, given the aforementioned purported mechanisms for the improving effects of L-carnitine/synbiotics on weight or metabolic parameters, it could be conceived that concomitant supplementation of L-carnitine and synbiotics may confer more pronounced impacts on these indicators, potentially through simultaneous modulation of energy homeostasis (8, 30), increasing fatty acid oxidation (8, 30), reducing adipogenesis or stimulating adipocyte lipolysis (21, 30), alleviating insulin resistance and glucose homeostasis (10, 31, 33), or attenuating systemic inflammation (56, 57), in a complementary or synergistic manner probably mediated through concurrent targeting of metabolic/inflammatory signaling pathways including CPT-Ia (20, 21), PDHC (8, 19), PPAR- (21, 31, 37), AMPK (30, 37), or NF-B (31, 34)

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