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Statistical analysis In this study, all the tests were conducted in triplicates and findings were given as the average of experiments with standard deviation (SD)

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Comprehensive safety studies spanning six months in rats (up to 100 mg/kg/day) and nine months in cynomolgus monkeys (up to 50 mg/kg/day) revealed no adverse findings, with NOAEL reaching the highest applied dosages

doi: 10.18632/aging.202378 Summary Keywords bibliometrics, brain aging, machine learning, selenoproteins, SEPHS2, SP1 Citation Liu S, Yan B, Gao H, Zhang L, Zhang Z, Liu Y, Chen F and Lei P (2026) Integrative bibliometric and transcriptomic analyses identify selenium-associated molecular signatures in the aging brain