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3.3 Dendritic cells Dendritic cells (DCs) are essential antigen-presenting cells that orchestrate immune responses by modulating T cell activation and differentiation, serving as a crucial connection between innate and adaptive immunity

For example, the activation markers CD69, CD83, LAG3, IL-2RA/B, TFRC, TNFRSF4/9/18 and CTLA4 were highly enriched (Fig

Low fermentable, oligo-, di-, mono-saccharides and polyol diet in the treatment of irritable bowel syndrome: A systematic review and meta-analysis

In terms of clinical outcomes, T2DM patients with MASLD have a 15% incidence of cirrhosis and a 7% incidence of hepatocellular carcinoma (HCC) within 10 years, alongside a 2.3-fold increased risk of cardiovascular events, underscoring the synergistic harm of multi-system metabolic dysregulation 9,10

The endocannabinoid system in aging The endocannabinoid system undergoes an unequivocal transition during aging across species (Bilkei-Gorzo, 2012