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Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts

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Acid-labile subunit (ALS) and IGFBP-3 are two proteins that bind IGF-I (~90% of total serum IGF-I) in a ternary complex which transports and prolong IGF-I half-life in circulation[23]