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85 Thus, these ferroptotic T cells are unable to proliferate and have reduced function against the acute lymphoblastic choriomeningitis virus and Leishmania major parasites, suggesting that Gpx4 is required for maintaining T cellmediated immunity by protecting the cells against ferroptosis

Although the natural substrate for Pf CRT has been proposed to include host-derived peptides of 411 residues 52 , the uptake kinetics in Xenopus oocytes is slow and yet to be validated using purified components