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Description

Norppa H, Tursi F, Pfaeffli P, Maeki-Paakkanen J, & Jaerventaus H (1985) Chromosome damage induced by vinyl acetate through in vitro formation of acetaldehyde in human lymphocytes and Chinese hamster ovary cells

Chronic kidney disease In: VaidyaSR, editor

The enzymatic reaction generally catalyzes the oxidation of PUFAs with the involvement of LOX to produce PE-PUFA-OOH and its derivatives and reactive aldehydes, including Malondialdehyde (MDA) and 4-hydroxynonenal (4HNE), which in turn induce ferroptosis, but these aldehydes, in turn, lead to impaired nucleic acid and protein functions (Pope and Dixon, 2023)