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Endocrinology 157:en20151709

Melanocytes on these cells produce and distribute melanin (a pigment that determines our natural hair color) which is then transferred to the keratinocytes that make up the cells in the hair shaft

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Previous studies have reported that Nrf2 deficient mice developed vacuolar (spongiform) leukoencephalopathy along with extensive astrogliosis, revealing a possible physiological role for Nrf2 in maintaining myelin in the central nervous system (Hubbs et al., 2007)