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This phased structure reduces the likelihood of toxin recirculation and improves tolerability by prioritizing containment and clearance rather than intensity

This article is part of the Topical Collection on Naturopathy, Nanotechnology, Nutraceuticals, and Immunotherapy in Cancer Research Rights and permissions About this article Cite this article Patil, S., Mohite, B.V., Marathe, K.R

This process results in the downregulation of epithelial cadherin (E-cadherin or cadherin-1) while simultaneously enhancing the expression of neural cadherin (N-cadherin or cadherin-2) and vimentin, an intermediate filament protein (Radisky et al