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At this stage, researchers study how well the treatment works and how safe it is in a much larger group of people over a longer period

Heme catabolism by tumor-associated macrophages controls metastasis formation

A small IV catheter is placed in your arm, and the nutrients flow directly into your bloodstream over 30-60 minutes

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An epigenome-wide association study involving 32 TRD patients undergoing ECT found longitudinal methylation changes at different CpG sites and gene regions (e.g., in FAM20C, IQCE, RUNX3 loci) that were associated with clinical improvement, though these results did not survive correction for multiple comparisons