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77,78 Comprehensive research on the risk factors for DN is limited, particularly concerning the genetic and viral infection influences on PDPN

52 In addition, inositol compounds called inositol phosphates act as second messengers to several hormones, including insulin and FSH, by transmitting external signals to the working interior of cells

P., Schiff, J

PARK2 mice had significantly higher normalized concentrations of Cyt-c (4.69 0.48 SEM, p = 0.03), 4-HNE (23.64 2.84 SEM, p = 0.03), Ox-LDL (8.02 0.82 SEM, p = 0.02), AGEs (9.84 1.13 SEM, p = 0.007) and TNF- (83.89 7.7 SEM, p = 0.002) compared to Wt mice (Cyt-c 2.88 0.38 SEM, 4-HNE 12.79 1.46 SEM, Ox-LDL 4.14 0.63 SEM, AGEs 3.37 0.67 SEM, TNF- 25.14 4.0 SEM) (Fig