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O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy

Luc JG, Antonoff MB , Rush G, Joyce C, Robinson E, Dunning J, Nguyen TC

Recent evidence suggests it may also impair cognitive functioning, with symptoms like memory lapses and difficulty concentrating often described as brain Key Points Lay Summary Laparoscopic port site complications

Correspondingly, caspase-3 (pro-apoptotic proteins) activity in -viniferin-treated hepatocytes was measured at only 7.1% following 24 h exposure, compared with significantly higher activation in untreated or vincristine-only groups, demonstrating effective inhibition of the execution phase of apoptosis

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