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A double-blind randomized controlled trial of infliximab associated with prednisolone in acute alcoholic hepatitis

13.3 Immunomodulatory mechanisms and novel applications Curcumin shifts macrophages from pro-inflammatory (M1) to anti-inflammatory (M2) phenotypes by suppressing TLR4/NF-B and JAK-STAT pathways, reducing IL-6, TNF-, and nitric oxide production