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Cayman Chemical offers several endoperoxides that act as ferroptosis inducers by oxidizing Fe 2+ , which promotes the production of lipid ROS

Miller RA, Harrison DE, Astle CM, Fernandez E, Flurkey K, Han M, Javors MA, Li X, Nadon NL, Nelson JF, Pletcher S, Salmon AB, Sharp ZD, Van Roekel S, Winkleman L, Strong R

Drugs metabolized via the CYP3A metabolic pathway interfere with CsA and tacrolimus metabolism, which can result in altered blood concentrations

Therefore, the present review provides a comprehensive overview of potential therapeutic targets provided by ferroptosis-related pathways in stroke, providing new insights into how ferroptosis can be exploited to treat stroke