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Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

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Gene set enrichment analysis (GSEA) was performed by the JAVA program ( using KEGG v7.0

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Increased Risk of Malignancy Inform patients about the increased background risk of malignancies in HIV-positive patients and for patients with a history of neoplasms, inform them about the risk of malignancy reoccurrence [see Warnings and Precautions (5.1)]