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Immunohistochemistry For immunohistochemical analysis of MBP and 4,6-diamidino-2-phenylindole (DAPI), tissue was fixed on slides with 4% paraformaldehyde for 20 min at room temperature, followed by three washes of 1 PBS

Central European Journal of Urology , 68 (3), 330

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Activation of Tissue Remodeling Proteases GHK-Cu activates matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in a balanced way that facilitates controlled extracellular matrix remodeling breaking down damaged collagen and replacing it with new, organized fibrillar collagen rather than scar tissue