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Description

Further experiments found that low-dose berberine can promote cell survival and antioxidant effects by up-regulating PI3K/AKT/Bcl-2 and Nrf2/HO-1 signal pathways

Aksentijevic, S.Y

Therefore, better understanding of the mechanisms of disordered innate immunity, including immune complex-mediated complement activation, adaptive immune responses against self-antigens, and abnormal cytokine networks may open up new avenues to restore immunologic homeostasis (Fig