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Description

Biomaterials 274 , 120875 (2021)

Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies

To rationally screen the activity of covalent inhibitors, small molecules containing cysteine thiols from GSH can be used to mimic thiols on target proteins in vivo, allowing us to assess the warhead activity of covalent inhibitors such as acrylamide using our established GSH binding experimental model