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When administered through injections, nasal sprays, or topical formulations, peptides bind to receptors that signal regeneration, fat metabolism, or anti-inflammatory responses

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The main pathological features of AD include the accumulation of -amyloid (A) forming extracellular senile plaques (SPs) and the hyperphosphorylation of the microtubule-associated protein tau (MAPT) forming intracellular neurofibrillary tangles (NFTs) (Graff-Radford et al., 2021)

Meanwhile, SYPa presynaptic vesicle markeris widely utilized in studies on synaptic damage and regeneration

and ergothioneine has alternately been suggested as a vitamin (Reference Paul and Snyder5) , longevity vitamin (Reference Ames8) and nutraceutical (Reference Borodina, Kenny and McCarthy6)