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One reason for this is that the level of glutathione will fluctuate throughout the day from its lowest in the early morning to depletion from routine exposure to toxic substances (like alcohol), pathogens, cigarette smoke, car exhaust, drugs, certain foods, stress level, illness, and many similar factors, so repeated testing could be required to set a baseline

Raphalen, J

Safety concerns, including hypokalemia, sedation, and teratogenicity, also restrict use

Among these effects, the impairment of the peripheral nervous system by chemotherapeutic agents results in peripheral neuropathy, a condition referred to as chemotherapy-induced peripheral neuropathy (CIPN)

Yanicke, S