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Ralph DJ, Hughes T, Lees WR, Pryor JP

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Sphingolipidomic analysis uncovered significant SL composition changes throughout development, with SMs/GluCers ratios dramatically increasing from larva to adult stage whereas total sphingolipid levels exhibiting opposing trends

It is noteworthy that all enrolled children demonstrated relatively low BMI values at baseline, reflecting the high prevalence of protein-energy wasting and growth impairment among pediatric patients receiving maintenance hemodialysis