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However, this insertion seems to be specific to vertebrates and is absent in photosynthetic organisms, which suggests a different organization

Brambilla P, Hardan A, di Nemi SU, Perez J, Soares JC, Barale F

Therefore, ITM treatment 17 days before TET did not enhance the synchronization success, but it did result in increased conception rates (embryo survival) at both 23 and 48 days after TET

Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling