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By integrating these pharmacological strategies, OSCs with otherwise limited systemic exposure may become viable candidates for both antimicrobial and host-directed clinical applicationsbridging the gap between in vitro promise and in vivo reality

10.1038/s41551-019-0369-4 42 DonnellyR

Unlike IGF-1 LR3, which has a long half-life (2030 hours) and systemic activity, IGF-DES has a significantly shorter half-life (2030 minutes) but an intense localized effect

the safety of biologics even with such a combination is excellent

Contributes to the neutralisation of free radicals: As a potent antioxidant, Glutathione helps combat free radicals that can lead to premature ageing and cellular damage