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doi: 10.1016/j.intimp.2014.11.003 265 KaramMCMerckbawiRSalmanSMobasheriA

MOTS-C: Mitochondrial peptide that regulates cellular energy, fat oxidation, and metabolic balance

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However, some individuals report experiences that suggest possible associations between B12 and anxiety-like symptoms in certain contexts: High-dose supplementation : Some individuals report feeling 'overstimulated' or experiencing changes in energy levels when initiating B12 supplements