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People with RLS experience an irresistible urge to move their legs, which is typically accompanied by aching, itching, or crawling sensations

Ensuring adequate intake of B12-rich foods or considering supplements is essential for these individuals

If your goal is weight management, your provider can help determine whether B12 support fits into your broader wellness plan

In a further aspect of the invention, one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that modulate intracellular NAD+ levels to provide muscular therapy is contacted with a cell expressing NNMT followed by contacting said cell expressing NNMT one or more NNMT inhibitors (such as a cation of Formula I or IA, or otherwise disclosed herein)

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