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Clinical trials demonstrate behavioral improvements and significant biological activity, with minimal adverse effects, supporting the safety profile of SFN

GCH1/BH4 axis The GTP cyclohydrolase-1 (GCH1)/Tetrahydrobiopterin (BH4) axis was deemed to be another independent pathway in the regulation of ferroptosis in several recent studies which performed the genome-wide screen (93, 94)

Another study also reported that the use of CuO-NPs can affect hepatic, renal, cardiac, and neural organs by altering the structure and physiology of those organs due to increased production of oxidative stress

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& Saw, S.-M