hypothesis glutathione persister cells

hypothesis glutathione persister cells Drug-tolerant cancer are vulnerable to GPX4 inhibition Vaccinia-related kinase 2 inhibition elicits

Name: hypothesis glutathione persister cells Drug-tolerant cancer are vulnerable to GPX4 inhibition Vaccinia-related kinase 2 inhibition elicits
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Vaccinia related kinase 2 inhibition elicits vulnerability of glutathione metabolism in pancreatic cancer Cell Death & Disease JCI Insight Mitochondrial metabolic rewiring sensitizes mTORC1 inhibitor persister cells to cuproptosis Ferroptosis: Opportunities and Challenges in Cancer Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death JCI CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione GPX4

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doi: 10.1016/j.metop.2025.100423

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