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Temperature and time Storage conditions influence reaction kinetics, solubility, and assembly pathways

Inconsistent dosing, varying between under and over, disrupts the steady-state concentrations many peptides require

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Ann Surg 229:713720 Hijikawa T, Kaibori M, Uchida Y et al (2008) Insulin-like growth factor 1 prevents liver injury through the inhibition of TNF-alpha and iNOS induction in D-galactosamine and LPS-treated rats