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Metabolic effect of pancreatoduodenectomy: Resolution of diabetes mellitus after surgery

Oxysterol responsive protein levels including fatty acids synthetase (Fas) and Acetyl CoA-carboxylase (Acc) were correlated with increased Srebp-1 mRNA levels in the StarD5 -/- mice liver

The former mechanism is preferred because RS scavengers can be consumed during the reaction and may generate toxic radicals derived from the chelators (Halliwell and Gutteridge, 2015)