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Methods Patients and samples A total of 18 skin biopsy samples was included: Ten samples from control patients and eight samples from psoriasis patients

Mechanistically, DOX-triggered JNK/Bcl-2Beclin-1 signaling and selective forms of autophagy such as mitophagy remove damaged mitochondria, lowering lipid-ROS and dampening lipid peroxidation, thereby antagonizing ferroptosis as an escape route from DOX cytotoxicity

Deutsche Wirtschaftspolitik: der Weg der Sozialen Markt-wirtschaft

Oxidative stress contributes to metastasis by influencing multiple steps of the metastatic cascade, including epithelial-mesenchymal transition (EMT), invasion, intravasation, survival in the circulation, extravasation, and colonization of distant organs [118]