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Moreover, the dual goals of ensuring safety and environmental responsibility by curbing water wastage are addressed

doi: 10.3233/JAD-220640 55 HuL

The key pathophysiological downstream effect of GBA mutations is decreased glucocerebrosidase (GCase) activity and lysosomal dysfunction and experimental studies have shown a reciprocal relationship of GCase activity and -synuclein aggregation [191, 192]