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Parker, V

PMID: 36457729

(2) the ability of the TJ to selectively allow paracellular transport of certain ion species acting as ion channel and (3) the ability of the TJs to maintain cell polarity, by blocking the free diffusion of proteins and lipids between the apical and basolateral domains of the plasma membrane

The drug stops working as effectively around the 3-month mark due to tolerance

For volumes below 0.02ml, increase your reconstitution concentration rather than attempting to measure smaller volumes, as surface tension and dead space retention in the needle hub introduce 1525% dose loss at these scales regardless of syringe quality