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The correlation between mitochondria-associated endoplasmic reticulum membranes (MAMs) and Ca2+ transport in the pathogenesis of diseases

doi: 10.1038/nrc2981 2 BoroughsLKDeBerardinisRJ

This suggests the importance of maintaining the balance of mitochondrial dynamics

Indeed, -actin was detected by Retromer and Retriever BioID1s, but not in BioID1-HRS, consistent with the known segregation of branched filamentous actin with the retrieval sub-domain (Supplementary Fig

NFE2L2 promoter variants particularly the -617C/A, -651G/A, and -653A/G haplotypes that reduce NRF2 transcription produce a transcription factor that is present in lower amounts before stress and therefore generates a smaller ARE-driven gene expression response when oxidative stress is sensed