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The study also highlighted AOD9604s influence on fat metabolism and energy expenditure, and its interaction with 3-adrenergic pathways [2]

3 The latter affects blood formation, leading to anaemia, a hallmark sign of B12 deficiency

While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

Its temporary inclusion on World Anti-doping Agencys monitoring list underscores persistent safety and ethical considerations, particularly concerning unsupervised administration and uncontrolled online distribution [32]