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But this can be very difficult to achieve

4.6 Overcoming challenges in translating natural compounds into clinical applications Despite promising findings, translating the therapeutic potential of natural compounds into clinical practice presents several key challenges

Some more sensitive compounds don't tolerate the benzyl alcohol preservative well and are better suited to preservative-free sterile water or saline, even though this typically means the reconstituted solution should be used sooner rather than stored for weeks

Aging, drinking too much alcohol, low stomach acid, certain medications that affect absorption, and chronic inflammation in the stomach known as atrophic gastritis can all leave you susceptible to a deficiency