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Large-scale survey studies that collect patient-reported treatment outcomes together with patients demographic and clinical characteristicssuch as comorbidities, clinical signs, symptoms, and disease severityare particularly effective at determining whether certain treatments work for specific subsets of patients

Elomda AM, Saad MF, Saeed AM, Elsayed A, Abass AO, Safaa HM, et al

3 The SLC2A9 gene, which encodes the fructose/urate co-transporter GLUT9, has been implicated in the greater number of Mori and Pacific peoples living with gout (see: The burden of gout is more severe among Mori and Pacific peoples)

This result was further confirmed by western blot in U2OS cells, where NSD2 was undetectable upon treatment with 300 nM UNC12149 for 6 h (Supplementary Fig

Seeing Yorkshire and Cumbria transformed into scenes from Waterworld, only with flat caps and wellies rather than animal skin capes, might have been mildly thrilling for the TV helicopters, but it was surely a sign that we should be constructing bigger flood barriers and building new homes on ever higher ground