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866 Excitatory amino acid transporter 1(EAAT1) in senescent cartilage membranes can increase intracellular glutamate levels and activate the GSH synthesis system to combat ferroptosis

In contrast, obesity may be associated with increased circulating prolactin levels, which are potentially mediated by adipose tissue expansion, enhanced aromatase-dependent estrogen production, and chronic low-grade systemic inflammation

References Anderson, J.M., et al

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Meanwhile, the NFB pathway regulates osteoclastspecific genes such as the osteoclastassociated receptor ( Oscar ), nuclear factor of activated T cells, cytoplasmic 1 ( Nfatc1 ), tartrateresistant acid phosphatase ( Trap ), and cathepsin K ( CatK ) [55]