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KO has various benefits, including antioxidative, anti-inflammatory, metabolic regulatory, neuroprotective, and gut microbiome modulatory effects

So, why do cancer cells exhibit aerobic glycolysis, i.e., the Warburg effect, which is essentially the manifestation of an abolished Pasteur effect, despite provision of citrate in the cytosol by multiple routes

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Nature.1999

Alessandri C et al (2017) CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjgrens syndrome patients and correlates with focus score and disease activity