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These cells were extracted from tumors coming from Th- MYCN transgenic mice over-expressing MYCN gene under the control of the tyrosine hydroxylase promoter

Zachrisson I, Brismar K, Carlsson-Skwirut C, Dahlquist G, Wallensteen M, Bang P

Inhibition of Lipogenesis (The Pull): It inhibits Lipoprotein Lipase (LPL) and Acetyl-CoA Carboxylase (ACC), preventing the uptake of dietary fat and the synthesis of new triglycerides

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While blood vessel compression is the most common cause, there are numerous alternative possibilities