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Lineage tracing experiments further demonstrated that Lgr5 -positive supporting cells can mitotically regenerate hair cells and that -catenin stabilization augmented both the mitotic response and the extent of hair cell regeneration (Wang et al., in press)

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49,50 Glutamate is the main neurotransmitter for increasing nerve excitability, while gamma-aminobutyric acid (GABA) is the main inhibitor of nerve signal transmission