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[86], which investigated tramadol (50400 mg) in a large cohort of patients

In vivo, hypoxanthine is formed by the dephosphorylation and deamination of ATP and is a hallmark of hypoxia-induced mitochondrial dysfunction

Based on emerging evidence, we propose a precision medicine approach that incorporates ferroptosis subtyping, multi-omics analysis, and targeted delivery systems

Manipulating methionine to enhance T cell anti-tumor immunity To date, many studies have sought to enhance anti-tumor responses in solid tumors by modulating methionine metabolism (74, 114118, 120)

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