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Blood 118(21):1613, 2011

Although the body naturally produces glutathione, factors like stress, pollution, poor diet, and aging can deplete its levels

While it is widely accepted that bortezomib typically does not penetrate the blood-brain barrier under normal conditions, it is plausible that in chronic brain inflammation and impaired blood-brain barrier, proteasome inhibition may reach both intrathecal and parenchymal plasma cells within the central nervous system [43]

glutathione, formalin, thiobarbituric acid (TBA), and dimethyl sulfoxide (DMSO) (Hi-Media Lab Pvt

Nat Rev Immunol (2010) 10(2):89.10.1038/nri2691 85 MartinonFMayorATschoppJ