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In contrast, a modest level of ROS is crucial for maintaining proper biological functions

Genetic modulation of hormone levels and life span in hybrids between laboratory and wild-derived mice

Science (1994) 264(5164):141521.10.1126/science.8197455 98 DarnellJEJr

Mol Biol Cell (2003) 14(4):144859.10.1091/mbc.E02-06-0342 82 UngureanuDWuJPekkalaTNiranjanYYoungCJensenONet alThe pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling