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The Role of Chronic Inflammation in Polycystic Ovarian Syndrome-A Systematic Review and Meta-Analysis

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Short-chain fatty acids (SCFAs) are metabolites secreted by intestinal microbiota during the fermentation of dietary fiber, mainly including butyrate, acetate and propionate (the ratio is 60:20:20), which can affect immune regulation and have anti-inflammatory effects [29]

Sun et al (98) demonstrated that intracellular lactate overload under prolonged ischemia inactivates the AMPK/NRF2/GPX4 protective axis, thereby promoting myocardial ferroptosis and exacerbating cardiac injury

In particular, we did not observe increases in the reactive astrocyte marker, S100beta, in whole brain lysates assessed by western blotting at 72h post-TBI