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Nicotine and the Brain: How Nicotine Affects the Brain HealthyPlace Understanding how habits work, especially with smoking, requires looking at the brain's reward system and how it forms automatic behaviors. At the heart of this process is dopamine, a neurotransmitter responsible for Smoking And Your Brain: The Negative Effects You Should Know Smokefree Alarming Study: Smoking Causes Brain Shrinkage It Sounds Bad, and It Is Bad Cigarette smoking and thinning of the brain's cortex PMC

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