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Expression of precursor molecules occurs predominantly in neurons where they are stored in large granular vesicles in the cytoplasm and released upon stimulation [21, 23]

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In the TME, tumor cells and cDC1s compete for glutamine uptake through the SLC38A2 transporter (33, 86)

Its also found in hundreds of over-the-counter and prescription medications , increasing the risk of accidental overdose

It promotes the expression of FSP1, reduces cellular level of Fe 2+ , ferritin heavy chain, and MDA, increases GPX4, and GSH, inhibits lipid peroxidation and cell ferroptosis, enhances the vitality of renal tubular cells, and alleviates AKI in septic rats (179)