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This observation suggests that PG is natively present in Lgt, as revealed by the crystal structure, and that prior binding of the acceptor prolipoprotein substrate is not required for the binding of the donor-substrate PG

[PubMed: 10964930] 698

3) and the absence of any renal drug transporters contributing to renal excretion as suggested from the in vitro study, indicates that, more specifically, elimination of pudexacianinium can be explained almost entirely by glomerular filtration

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