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296,297 Thus, HDAC inhibition represents a promising approach for the treatment of AD

Chat et al., 2023)

Furthermore, oxidative stress and hence free radical damage to mitochondria and other cellular structures deplete cardiomyocyte energy stores

Similarly, ROS also enhance inflammation through NF-B pathway activation, leading to IB degradation, NF-B nuclear translocation, and transcriptional upregulation of inflammatory mediators [93, 94]